Warm, creamy, and packed with cozy flavors, this Chicken Bubble Biscuit Bake Casserole is the ultimate comfort food for busy weeknights or weekend indulgence.

The combination of tender chicken, fluffy biscuits, and melty cheese creates a bubbling, golden-topped dish that satisfies every craving with minimal effort and maximum flavor.

What You’ll Need for This Chicken Bubble Biscuit Bake Casserole

  • Cooked and chopped chicken – The hearty backbone of the dish, offering protein and a satisfying bite in every forkful.
  • Cream of chicken soup – Adds rich, creamy depth and ties all the ingredients together into a luscious, cohesive filling.
  • Sour cream – Brings a welcome tang that balances the richness of the casserole beautifully.
  • Grated cheese – Melts into gooey perfection while also crisping on top for an irresistible finish.
  • Ranch dressing mix – Infuses the dish with bold, zesty flavor and savory herbs in every bite.
  • Cooked and chopped bacon – Adds smoky crunch and a salty punch that complements the creamy base.
  • Refrigerated Grands Jr. biscuits – The “bubble” in the bake, these tender biscuit pieces puff up and soak in the savory sauce while baking.

How to Bring This Biscuit Casserole to Life

Start by preheating your oven and prepping your baking dish with a light coat of cooking spray. This ensures your casserole comes out cleanly with every gooey scoop.

In a large bowl, stir together the chicken, creamy soup, sour cream, cheese, Ranch mix, and bacon until everything is smoothly combined. Chop the biscuits into quarters and gently fold them into the mix.

Once the mixture is well coated and evenly combined, spread it in your baking dish. Sprinkle more cheese over the top to create that bubbling, golden crust. Bake until the casserole is set and gloriously browned on top.

Extra Delicious – Tips & Variations to Try

To elevate the flavor even further, consider using a blend of cheddar and Monterey Jack cheese for added creaminess and depth. For a bit of heat, stir in a handful of chopped jalapeños or a pinch of cayenne pepper.

You can swap the cream of chicken soup with cream of mushroom for an earthier flavor profile. Not a fan of Ranch? Try Italian seasoning or a garlic and herb blend for a different twist.

If you’re feeding a crowd or looking for a heartier version, stir in a cup of steamed broccoli florets or sautéed mushrooms for added bulk and texture.

Storing the Goodness – Save Now, Savor Later

To store leftovers, let the casserole cool completely before transferring it into an airtight container. It will keep in the fridge for up to 3 days.

For longer storage, freeze individual portions wrapped tightly in foil and stored in a freezer bag for up to 2 months. Reheat in the oven at 350°F until warmed through to retain that crispy biscuit topping.

Chicken Bubble Biscuit Bake Casserole

This creamy and savory casserole combines tender chicken, fluffy biscuit pieces, and a cheesy, ranch-seasoned base for a hearty and comforting dish that’s ready in under an hour.
Prep Time 15 minutes
Cook Time 25 minutes
Total Time 40 minutes

Ingredients
  

  • 1/4 cup cooked and chopped bacon
  • 2 tablespoons Ranch dressing mix
  • 1 cup grated cheese plus additional for topping
  • 2 cans cream of chicken soup
  • 3 cups cooked and chopped chicken
  • 1 1/2 cups sour cream
  • 1 12 oz can of refrigerator Grands Jr Biscuits

Instructions
 

  • Preheat the oven to 350°F and prepare a 9 x 13-inch baking dish by coating it lightly with cooking spray.
  • In a spacious mixing bowl, thoroughly blend the chicken, soup, sour cream, 1 cup of cheese, Ranch dressing mix, and bacon until the mixture is evenly combined.
  • Divide each biscuit into four equal parts and gently incorporate them into the chicken blend, ensuring even distribution.
  • Spoon the prepared mixture into the greased baking dish and smooth the top to create an even layer.
  • Generously sprinkle additional grated cheese over the surface of the casserole.
  • Place the dish in the oven and bake for 25 to 35 minutes, or until the top is a rich golden hue and the contents are bubbling. Serve immediately while hot.

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